Michael D Deel
Michael D Deel

Michael D Deel

Assistant Professor of Pediatrics

Overview

Dr. Deel is a clinician scientist in Pediatric Hematology/Oncology. In addition to caring for pediatric patients with hematologic disorders or malignancy, his research focuses on finding novel ways to target fusion-positive pediatric sarcomas. His current work focuses on understanding the gene regulation and molecular pathways responsible for alveolar rhabdomyosarcoma, which is among the most difficult to cure pediatric cancers. Alveolar rhabdomyosarcoma is driven by chromosomal translocations t(2;13) or t(1;13) that result in oncogenic transcription factors encoding for PAX3/7-FOXO1 fusion proteins. The PAX3/7-FOXO1 oncogenes are currently not viable therapeutic targets. Using a variety of cell culture and murine models, Dr. Deel is investigating genes and pathways that regulate or coordinate PAX3/7-FOXO1-mediated tumorigenesis.

Positions

Assistant Professor of Pediatrics in the School of Medicine

2021 School of Medicine

Member of the Duke Cancer Institute in the School of Medicine

2018 School of Medicine

Education

M.D. 2010

2010 Marshall University, Joan C. Edwards School of Medicine

Internshipand Residency, PEDIATRICS/UNIVERSITY OF LOUISVILLE

2013 University of Louisville

Pediatric Hematology/Oncology Fellowship, PEDIATRICS/DUKE UNIVERSITY SCHOOL OF MEDICINE

2016 Duke University, School of Medicine

Advanced Pediatric/Oncology Research Training, PEDIATRICS/DUKE UNIVERSITY SCHOOL OF MEDICINE

2017 Duke University, School of Medicine

Publications, Grants & Awards

DCI Centers, Cancer Types & Labs

Offices & Contact

Duke University Medical Center
Durham, NC
27710
Duke University
Durham, NC
27710