Breast Cancer

Duke Chief of Breast Surgery Eun Sil (Shelley) Hwang, MD, Mary and Deryl Hart Distinguished Professor of Surgery, is on the Breast Cancer – Local/Regional/Adjuvant Scientific Program Committee.

ABSTRACTS

*Duke authors bolded

Ipsilateral invasive cancer risk after diagnosis with ductal carcinoma in situ (DCIS): Comparison of patients with and without index surgery
SESSION
Breast Cancer—Local/Regional/Adjuvant
AUTHOR(S)
Marc D Ryser, Laura Hendrix, Samantha M. Thomas, Thomas Lynch, Anne McCarthy, Zahed Mohammed, Amanda B. Francescatti, Elizabeth S. Frank, Ann H. Partridge, Alastair Mark Thompson, Terry Hyslop, Eun-Sil Shelley Hwang
ABSTRACT / POSTER 519 ● 11

Identification of pathogenic ROS1 alterations in cell-free DNA (cfDNA) from patients with breast cancer
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Jeremy Meyer Force, Mary Love Taylor, Leylah Drusbosky, Jennifer Yen, Paul Kelly Marcom, Carey K. Anders, Jeffrey R Marks.
ABSTRACT / POSTER 1031 ● 116

Disparities in receipt of and time to adjuvant therapy after lumpectomy.
SESSION
Breast Cancer—Local/Regional/Adjuvant
AUTHOR(S)
Irene Dankwa-Mullan, M. Christopher Roebuck, Joseph Tkacz, Oluwadamilola Motunrayo Fayanju, Yi Ren, Gretchen Purcell Jackson, Yull Edwin Arriaga
ABSTRACT / POSTER 534 ● 26

Understanding and predicting fatigue, cardiovascular (CV) decline & events after breast cancer treatment (UPBEAT): A prospective multi-center wake forest NCORP research-base study.
SESSION
Breast Cancer—Local/Regional/Adjuvant
AUTHOR(S)
Susan Faye Dent, Kerryn Reding, Glenn Jay Lesser, Heidi D. Klepin, Lynne I. Wagner, Dalane Kitzman, Peter H. Brubaker, Shannon Mihalko, Nancy E. Avis, Karen Marie Winkfield, Bonnie Ky, Teresa Crotts, Robin Kikuchi, Tonya Calhoun, W. Gregory Hundley
ABSTRACT / POSTER TPS602 ● 94

Updated results from the phase IIIb complement-1 study of ribociclib (RIB) plus letrozole (LET) in the treatment of HR+, HER2-advanced breast cancer (ABC).
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Michelino De Laurentiis, Simona Borstnar, Mario Campone, Ellen Warner, Javier Salvador Bofill, William Jacot, Susan Faye Dent, Miguel Martin, Alistair E. Ring, Paul H. Cottu, Janice M. Lu, Eva Ciruelos, Hamdy A. Azim, Sanjoy Chatterjee, Katie Zhou, Jiwen Wu, Nii Ankrah, Claudio Zamagni
ABSTRACT / POSTER 1055 ● 140

Preliminary efficacy data of triple-negative breast cancer cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors.
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Navid Hafez, Hatem Hussein Soliman, Siqing Fu, Karen A. Gelmon, Albiruni Ryan Abdul Razak, Pamela N. Munster, Ulka N. Vaishampayan, Shumei Kato, Primo Lara, Elizabeth M. Swisher, Andrew B. Nixon, Abhijit Patel, Yu Shyr, S. Percy Ivy, Patricia LoRusso, Joseph W. Kim
ABSTRACT / POSTER 1077 ● 162

Trial in progress: A phase II open-label, randomized study of PARP inhibition (olaparib) either alone or in combination with anti-PD-L1 therapy (atezolizumab) in homologous DNA repair (HDR) deficient, locally advanced or metastatic non-HER2-positive breast cancer.
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Patricia LoRusso, Mary Josephine Paula Pilat, Cesar Augusto Santa-Maria, Roisin M. Connolly, Erin Elizabeth Roesch, Anosheh Afghahi, Hyo S. Han, Rita Nanda, Gerburg M. Wulf, Hadeel Assad, Haeseong Park, Elizabeth Claire Dees, Jeremy Meyer Force, Anne M. Noonan, Adam Brufsky, Vandana G Abramson, Barbara B. Haley, Saundra S. Buys, Elad Sharon, Kurt A. Schalper
ABSTRACT / POSTER TPS1102 ● 187

Tucatinib versus placebo added to trastuzumab and capecitabine for patients with previously treated HER2+ metastatic breast cancer with brain metastases (HER2CLIMB).
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Nancy U. Lin, Rashmi Krishna Murthy, Carey K. Anders, Virginia F. Borges, Sara A. Hurvitz, Sherene Loi, Vandana G Abramson, Philippe L. Bedard, Mafalda Oliveira, Amelia Bruce Zelnak, Michael DiGiovanna, Thomas Bachelot, Amy Jo Chien, Ruth O'Regan, Andrew M. Wardley, Volkmar Müller, Lisa A. Carey, Suzanne M. McGoldrick, Grace An, Eric P. Winer
ABSTRACT 1005

Results of a phase II randomized trial of cisplatin +/- veliparib in metastatic triple-negative breast cancer (TNBC) and/or germline BRCA-associated breast cancer (SWOG S1416).
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Priyanka Sharma, Eve Rodler, William E. Barlow, Julie Gralow, Shannon Leigh Huggins-Puhalla, Carey K. Anders, Lori J. Goldstein, Ursa Abigail Brown-Glaberman, Thu-Tam Huynh, Christopher Scott Szyarto, Andrew K. Godwin, Harsh B Pathak, Elizabeth M. Swisher, Marc R Radke, Kirsten M Timms, Danika L. Lew, Jieling Miao, Lajos Pusztai, Daniel F. Hayes, Gabriel N. Hortobagyi
ABSTRACT 1001

TBCRC 048: A phase II study of olaparib monotherapy in metastatic breast cancer patients with germline or somatic mutations in DNA damage response (DDR) pathway genes (Olaparib Expanded).
SESSION
Breast Cancer—Metastatic
AUTHOR(S)
Nadine M. Tung, Mark E. Robson, Steffen Ventz, Cesar Augusto Santa-Maria, Paul Kelly Marcom, Rita Nanda, Payal D Shah, Tarah Jean Ballinger, Eddy Shih-Hsin Yang, Michelle E. Melisko, Adam Brufsky, Shaveta Vinayak, Michelle Demeo, Colby Jenkins, Susan M. Domchek, Gerburg M. Wulf, Ian E. Krop, Antonio C. Wolff, Eric P. Winer, Judy Ellen Garber
ABSTRACT 1002

Blocking pro-invasive signaling and inflammatory activation in triple-negative breast cancer with nucleic-acid scavengers (NASs).
SESSION
Publication Only: Breast Cancer—Metastatic
AUTHOR(S)
Elias Eteshola, Karenia Landa, Eun-Sil Shelley Hwang, Smita Nair, Bruce Sullenger
ABSTRACT e13096

Real-word incidence and management of durable complete response in de novo metastatic HER2-positive breast cancer.
SESSION
Publication Only: Breast Cancer—Metastatic
AUTHOR(S)
Claire Elizabeth Powers Smith, Paul Kelly Marcom, Zahi Ibrahim Mitri
ABSTRACT e13017

Out-of-pocket cost of screening with breast MRI for women at high risk for breast cancer.
SESSION
Care Delivery and Regulatory Policy
AUTHOR(S)
I-Wen Pan, Kevin C. Oeffinger, Ya-Chen T. Shih
ABSTRACT / POSTER 2017 ● 9

Missing data in breast cancer: Relationship with survival in national databases.
SESSION
Publication Only: Health Services Research and Quality Improvement
AUTHOR(S)
Jennifer Kay Plichta, Christel N. Rushing, Holly C. Lewis, Dan G. Blazer, Terry Hyslop, Rachel Adams Greenup
ABSTRACT e19114

Can a brief multimedia intervention facilitate breast cancer patients’ communication about sexual health? Findings from a randomized controlled trial.
SESSION
Publication Only: Symptoms and Survivorship
AUTHOR(S)
Jennifer B. Reese, Mary Catherine Beach, Kristen A. Sorice, Whitney Pollard, Mary Beryl Daly, Elizabeth A. Handorf, Laura S Porter, James A. Tulsky, Stephen J Lepore
ABSTRACT e24179

Work loss and activity impairment due to duration of nausea and vomiting in patients with breast cancer receiving CINV prophylaxis.
SESSION
Publication Only: Symptoms and Survivorship
AUTHOR(S)
Lee S. Schwartzberg, Rudolph M. Navari, Kathryn Jean Ruddy, Thomas William LeBlanc, Rebecca Anne Clark-Snow, Rita S. Wickham, Gary Binder, William Bailey, Marco Turini, Ravi C. Potluri, Luke M. Schmerold, Eric Roeland,
ABSTRACT e24133