CGX1321-101 (Gastrointestinal Cancer)
What is the Purpose of this Study?
-Take the study drug, CGX1321, by mouth once a day
-Take zoledronic acid by I.V. once every 6 or 8 weeks
-Take daily supplements of vitamin D3 and calcium carbonate
-Give blood and urine samples
-Have regular CT or MRI scans
In addition, some people may also get pembrolizumab by I.V. once every 3 weeks.
Who Can Participate in this Study?
Adults with advanced gastrointestinal cancer who:
-Failed, refused, or are unsuited for standard-of-care treatment
What is Involved?
We are doing this study to see if the study drug, CGX1321, is safe and effective for fighting cancer.