Pediatric Clinical Trials

Pediatric Leukemia/MDS

If you would like to inquire about all open trials, please contact 919.684.3401.

12 trials identified.

AALL08B1 Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
Phase: N/A
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.684.3401
Reference Number: 00025867
View this trial at ClinicalTrials.gov

AALL0932 Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL)
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.684.3401
Reference Number: 00025879
View this trial at ClinicalTrials.gov

AAML1031 A Phase III Randomized Trial for Patients with de novo AML using Bortezomib (IND# 58443, NSC# 681239) and Sorafenib (BAY 43-9006, IND#69896, NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.684.3401
Reference Number: 00031615
View this trial at ClinicalTrials.gov

AALL1131 A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) including a Stratum Evaluating Dasatinib (IND#73789, NSC #732517) in Patients with Ph-like Tyrosine Kinase Inhibitor (TKI) Sensitive Mutations
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Pediatric Oncology Clinical Trials Office
Phone: 919.684.3401
Reference Number: 00034203
View this trial at ClinicalTrials.gov

ACCL1033 A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL
Phase: N/A
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.684.3401
Reference Number: 00053228
View this trial at ClinicalTrials.gov

CCTL019B2205J- A Phase II, single arm, multicenter trial to determine the efficacy and safety of CTL019 in pediatric patients with relapsed or refractory B-cell acute lymphoblastic leukemia
Phase: Phase II
Sponsor: External Investigator-Sponsored (External Med Ctr)
Principal Investigator: Paul Martin
Contact: Jennifer Baker, RN
Phone: 919.668.1100
Reference Number: 00057441
View this trial at ClinicalTrials.gov

AALL1231 A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T- Lymphoblastic Leukemia (T-ALL) and T- Lymphoblastic Lymphoma (T-LLy)
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.684.3401
Reference Number: 00059538
View this trial at ClinicalTrials.gov

AALL1331 Risk-Stratified Randomized Phase III Testing of Blinatumomab (IND#117467, NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL)
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Dr. Susan Kreissman
Phone: 919.6843401
Reference Number: 00060960
View this trial at ClinicalTrials.gov

A PHASE I/II STUDY OF THE SELECTIVE INHIBITOR OF NUCLEAR EXPORT SELINEXOR (KPT-330) IN COMBINATION WITH FLUDARABINE AND CYTARABINE IN PEDIATRIC PATIENTS WITH REFRACTORY OR RELAPSED LEUKEMIA OR MYELODYSPLASTIC SYNDROME IND#122,979
Phase: Phase II
Sponsor: External Investigator-Sponsored (External Med Ctr)
Principal Investigator: Daniel Wechsler
Contact: Dr. Daniel Wechsler
Phone: 919.684.3401
Reference Number: 00062654
View this trial at ClinicalTrials.gov

APEC14B1 Project:EveryChild A Registry, Eligibility Screening, Biology and Outcome Study
Phase: N/A
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Pediatric Oncology Clinical Trials Office
Phone: 919.684.3401
Reference Number: 00068349
View this trial at ClinicalTrials.gov

AAML1331 A Phase III Study for Patients with Newly Diagnosed Acute Promyelocytic Leukemia (APL) using Arsenic Trioxide and All-Trans Retinoic Acid
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Susan Kreissman, MD
Phone: 919.684.3401
Reference Number: 00069267
View this trial at ClinicalTrials.gov

AAML1531 Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome
Phase: Phase III
Sponsor: Cooperative Group Initiated
Principal Investigator: Susan Kreissman
Contact: Pediatric Oncology Clinical Trials Office
Phone: 919.684.3401
Reference Number: 00070111
View this trial at ClinicalTrials.gov