Hematologic Malignancies & Cellular Therapy

Overview

As leaders in hematologic oncology, stem cell & bone marrow transplantation, and immunotherapy, Duke Cancer Institute’s Hematologic Malignancies and Cellular Therapy (HMCT) program is internationally recognized for its novel approaches to treating leukemia, lymphoma, myeloma and other life threatening diseases.

Our Program’s mission is to promote health and improve lives by preventing, diagnosing, and treating these blood cancers through integrated, innovative, and holistic patient care, education, and research.

Treatment

Make An Appointment

Duke Hematologic Malignancies & Cellular Therapy Specialists provide comprehensive, multidisciplinary care for patients at the Duke Cancer Center and the Duke Adult Blood & Marrow Transplant Clinic.

To make an appointment, please call 919.684.8964.

Providers who see patients in the Hematologic Malignancies Clinic include David RizzieriCarlos DeCastroJoseph MooreThomas LeblancMatthew McKinneyLindsay ReinAhmed Galal, and Alexandra Stefanovic.

Providers who see patients in the ABMT Clinic include Mitchell HorwitzNelson ChaoGwynn LongCristina GasparettoYubin KangAnthony SungStefanie SarantopoulosTaewoong Choi, and Cristiana Costa.

Research

The Duke Hematologic Malignancies & Cellular Therapy (HMCT) Research Program is a multidisciplinary basic, translational, and clinical research program whose overall goal is to improve outcomes for patients with hematologic malignancies.

Our research program can be broadly divided into the following research areas: 

  • Basic research into the tumor microenvironment, bone marrow niche
  • Basic understanding of immunity, both inate and adaptive
  • Genomics, including a genomics core
  • Cellular therapies such as hematopoietic stem cells, adoptive immunotherapy with selected T cells, NK cells, dendritic cell vaccines, gamma delta T cells
  • Graft-versus-host disease and graft-versus-leukemia effects
  • Cell signaling pathways in normal and tumor cells

LEARN MORE

Clinical Trials

We offer our patients access to more than 50 active clinical trials specific to hematologic malignancies and transplantation.

These trials range from securely storing your medical information in an outcomes-reporting registry, to sample repositories, and to national clinical trials and investigator-initiated trials designed to prevent, detect, or treat your underlying disease with the most advanced treatment methods.

Your participation may help you and others in the future. 

Some of these trials are only offered at the Duke Cancer Institute. As a result, we offer a broad selection of treatment options to our patients, including some who are not considered candidates for treatment elsewhere. Your participation in a clinical trial may help you and others in the future. 

Search our active clinical trials related to the treatment of Leukemia and multiple myeloma, Lymphomas - Non-Hodgkin's lymphoma and Hodgkin's disease, and BMT and Cellular Therapies.

Additional Contacts

Gabriel Alcantara, MBA, Administrative Director
Phone: 919.668.2121

Julia Hoyle, Assistant Research Practice Manager
Phone: 919.668.1016

Blood Cancer Specialists

                                                                 We discover, develop and deliver the future of cancer care . . . now.

Leukemia & Myelodysplastic Syndromes Program
Carlos DeCastro, MD
Harry Erba, MD, PhD
Thomas Leblanc, MD 
David Rizzieri, MD
Donna Adams, NP
Sarah Chittenden, NP
Therese Hennig, PA

Myeloproliferative Neoplasms Program
Harry Erba, MD, PhD
Lindsay Rein, MD
Donna Adams, NP
Sarah Chittenden, NP

Lymphoma & Chronic Lymphocytic Leukemia Program
Danielle Brander, MD 
Ahmed Galal, MD
Matthew McKinney, MD
Alexandra Stefanovic, MD

Jie Wang, MD
Christopher Kelsey, MD (Rad Onc) 
Samantha Schmidtke, NP
Jennifer Snyder, NP

Chimeric Antigen Receptor T-Cell Program
Ahmed Galal, MD
Matthew McKinney, MD
David Rizzieri, MD
Jessica Harrison, PA
Therese Hennig, PA
Jennifer Snyder, NP
 
Multiple Myeloma Program
Taewoong Choi, MD
Cristiana Costa, DO
Cristina Gasparetto, MD
Yubin Kang, MD
Taylor Addis, NP
Anderson Garrett, NP
Emily Sellars, NP
Scott Winkel, PA

Adult Blood & Marrow Transplant Program
Nelson Chao, MD
Taewoong Choi, MD
Jessica Harrison, PA
Cristina Gasparetto, MD
Mitchell Horwitz, MD
Yubin Kang, MD
Gwynn Long, MD
Richard Lopez, MD
David Rizzieri, MD
Stefanie Sarantopoulos, MD, PhD
Anthony Sung, MD
Margaret “Peggy” Eren, NP
Tanya Helms, PA
Therese Hennig, PA
Kerry Minor, NP
Renee Nester, NP
Kristi Wiggins, NP
 
Hematologic Malignancies Program
Duke Cancer Center Raleigh

Suzanne Kirby, MD, PhD