The High-Throughput Screening (HTS) Shared Resource (a developing CCSG shared resource) provides reagents, infrastructure and expertise for screening of chemical, CRISPR, RNAi, and open reading frame (ORF) libraries. The screening platforms supported by the facility enable systematic, comprehensive interrogation of gene function or molecular processes that provide opportunities for discovery of new targets, lead compounds or biological insights. In addition, the shared resource provides assistance with custom functional genomics applications for low-throughput experiments.
The shared resource provides services in three major areas: compound screening, functional genetic screening and custom genetic perturbation services. Instrumentation is available for most quantitative assays in the form of multimodal plate readers and a Cellomics ArrayScan High-Content Screening (HCS) system.
Services and resources provided by the shared resource are available to all DCI members. Members interested in utilizing this resource should visit the website or contact So Young Kim, PhD. As a developing resource, the High-Throughput Screening Shared Resource does not currently maintain a fee schedule for DCI members, but offers priority access to these services to DCI members. For information on fees, please contact So Young Kim, PhD.
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