THIS SEMINAR SERIES HAS BEEN POSTPONED INDEFINITLY
The March DCI Seminar Series will be held on Wednesday, March 25, in the Trent Semans Center, Great Hall.
The guest speaker is Marie-Catherine Vozenin, PhD, HDR, head of Radiobiology, Lausanne University Hospital (CHUV/UNIL), and associate professor of Radiation Oncology at Lausanne University Hospital and University of Lausanne. Vozenin will present “Sometimes quicker is better – the emerging story of FLASH Radiation therapy for ultra-fast cancer treatment.”
Vozenin and her team have developed a novel modality of radiation therapy called FLASH-RT that minimizes normal tissue toxicity and eradicates tumors in various organs including the brain, lung and skin in various species including mice, zebrafish, pigs and cats. The protection of normal tissue by FLASH-RT was termed the FLASH effect, resulting in a series of investigations to characterize the mechanisms involved. Vozenin's team is working to secure the translation of FLASH-RT into clinical trials for human patients with cancer. This technology is currently in a phase one clinical trial with domestic cat patients with squamous cell carcinoma and a multi-center clinical trial in dogs with glioma.
Vozenin's research also includes work on combining radiotherapy and immunotherapy to improve treatment of lung and head and neck cancer and the contribution of RhoB to the pathogenesis of cardiac toxicity induced by anti-cancer treatments. She has authored numerous papers, including in Radiotherapy Oncology, Proceedings of the National Academy of Sciences, Science Translational Medicine, and Medical Physics.
Her research is funded under a number of grants, including a current NIH-P01 collaborative grant to investigate increasing the therapeutic index of brain tumor treatment through innovative FLASH radiotherapy.
Vozenin earned her PhD in Oncology/Radiobiology from South Paris XI University, Paris, in 1999 and her HDR in 2005.
From 2005 to 2009 she served as associated editor for the World Journal of Gastroenterology. Since 2017, she's been associate senior editor of the Journal of the American Society of Radiotherapy: Int J Radiat Oncol Biol Phys. In 2015, Vozenin was honored with the Osborne Award by the American Radiation Research Society.
Since 2018, Vozenin's been a member of the evaluation board of Inspire (H2020 project on Proton) and since 2017, she's been a member of the SSRPM evaluation committee (medical physicist certification, CH).
Vozenin's lecture begins at 8 a.m. and ends at 9 a.m. The March DCI Seminar Series is presented by the DCI Radiation Oncology and Imaging Program and is held in conjunction with Hematology Oncology Grand Rounds.