UNC Bladder (LCCC 1520)
What is the Purpose of this Study?
Who Can Participate in this Study?
Adult patients with muscle invasive bladder cancer who are planning to have a surgery to remove the bladder (cystectomy).
What is Involved?
If you choose to join this study, you will:
- Enter a screening period that includes a physical exam, imaging scans, surveys, and blood draws
Once you have completed the screening period, you will:
- Get the study drug pembrolizumab on day 1 of each 3 week cycle along with standard-of-care gemcitabine and cisplatin on days 1 and 8.
-- You will take study drugs for 12 weeks (4 cycles)
- Have blood draws, a physical exam, and be asked questions about the side effects you might had while taking the study drug
- Get a cystectomy (bladder removal surgery) after you have taken the study drug
-- After your cystectomy, you will return to clinic for a post-surgery visit where you will be asked about your side effects.
--Be followed for up to 5 years after your post-surgery visit. Each visit may include surveys about your quality of life, and imaging.