What is the Purpose of this Study?
If you choose to join this study, you will:
- Be randomly assigned (like flipping a coin) to 1 of 2 treatment groups
-- One group will receive the drug ibrutinib
-- The other group will receive placebo (an inactive substance)
What is the Condition Being Studied?
Large B-Cell Lymphoma that has returned after it was getting better
Who Can Participate in this Study?
Adults with Large B-Cell Lymphoma that has relapsed or not responded to treatment.
What is Involved?
We are doing this study to see how a drug called ibrutinib works in your body and against your cancer.
Alliance A051301: A Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma of the Activated B-Cell Subtype
George Barth Geller Distinguished Professor for Research in Cancer
View on ClinicalTrials.gov