What is the Purpose of this Study?
We are doing this study to learn if the study drug (entrectinib) is safe and will work in patients with advanced cancer with a gene mutation.
What is the Condition Being Studied?
Solid tumor cancer with specific gene mutations
Who Can Participate in this Study?
Adults diagnosed with solid tumor cancer that has a gene mutation (NTRK1/2/3, ROS1, or ALK gene rearrangement).
What is Involved?
If you choose to be in this study you will:
- Have blood drawn, and a possible tumor tissue biopsy
- Physical and eye exam
- Complete quality of life surveys
- Take study drug (entrectinib) by mouth every day
- Take part in this study until your disease worsens or your study doctor requests you to stop
An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements
View on ClinicalTrials.gov