TMIST Mammography Study (Breast Cancer Screening)

If you choose to join this study, you will:

• Be randomized (like the flip of a coin) to screening with Tomosynthesis Mammography (TM) or Digital Mammography (DM)

The frequency and number of screening mammograms will vary with your menopausal status and whether you have breast cancer risk factors.

• All premenopausal women will have annual screening

• Postmenopausal women will have screening every 2 years unless they have any specific risk factors

• Have either three-dimensional (3D) Tomosynthesis Mammography or two-dimensional (2D) Digital Mammography

• Get screened every year for four more years - for a total of five mammograms, or
• Every other year - for a total of three mammograms

• Be followed for 4.5 to 8 years

Breast cancer

Women aged 45 to 74

We are doing this study to compare two different screening mammography methods in pre- and post-menopausal women to understand whether one method is better than the other at finding life-threatening breast cancers.