What is the Purpose of this Study?
We are doing this study to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for low grade glioma in children and young adults is using a combination of carboplatin and vincristine.
This study will try to understand if treatment with carboplatin alone improves quality of life for patients with low grade glioma and their families.
What is the Condition Being Studied?
Brain cancer (low grade glioma)
Who Can Participate in this Study?
- Are less than 21 years old
- Are newly or previously diagnosed with a low grade brain tumor, such as glioma
What is Involved?
If you choose to join this study, you will:
-Be randomly assigned (like the flip of a coin) to get one of two treatments:
-- A combination of the chemotherapy drugs carboplatin and vincristine
-- The chemotherapy drug carboplatin by itself
A Phase III Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults with Previously Untreated Low Grade Glioma
Rory David Deutsch Distinguished Professor of Neuro-Oncology
View on ClinicalTrials.gov