ANBL1531 for High-Risk Neuroblastoma
What is the Purpose of this Study?
Who Can Participate in this Study?
Children and Adults with Neuroblastoma who:
- Are 1 year old and less than 30 years old
- Are able to tolerate peripheral blood stem cell collection
What is Involved?
If you choose to be in this study, you will:
- Be randomized (like drawing numbers out of a hat) to get either:
-- Group 1: Standard of care treatment
-- Group 2: Study drug 131I-MIBG and standard of care treatment
-- Group 3: Study drug 131I-MIBG and one stem cell transplant and standard of care chemotherapy
-- Group 4: Standard of care treatment
-- Group 5: Study drug Crizotinib plus standard of care treatment
- Have a scan and have tissue taken from your tumor sent for a test to see if it contains a specific gene
- Have standard treatment called induction therapy