MEM-288 (solid tumors)

What is the Purpose of this Study?

We are doing this study to find out if an experimental drug called MEM-288 (the study drug) is a safe and effective treatment for your cancer.

What is the Condition Being Studied?

Advanced Solid Tumors

Who Can Participate in the Study?

Adults diagnosed with the following cancers that have spread:

  • Non-small cell lung cancer (NSCLC)
  • Cutaneous squamous-cell carcinoma (cSCC)
  • Merkel cell carcinoma
  • Melanoma
  • Triple negative breast cancer (TNBC)
  • Pancreatic cancer
  • Head and neck cancer
Age Group
Adults

What is Involved?

If you choose to join this study, you will:

  • Take the study drug (MEM-288)
  • Provide tumor tissue
  • Have physical exams, blood draws, and give urine samples
  • Have imaging scans (CT and MRI)
  • Have heart tests (ECG)

Study Details

Full Title
Phase I Study of MEM-288 Oncolytic Virus Alone and in Combination with Nivolumab in Solid Tumors including Non-Small Cell Lung Cancer (NSCLC)
Principal Investigator
Headshot of Neal Edward Ready
Professor of Medicine
Protocol Number
IRB: PRO00109517
NCT: NCT05076760
Phase
Phase I
ClinicalTrials.gov
Enrollment Status
OPEN TO ACCRUAL
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