Understanding the mechanisms underlying the interplay between cellular and organismal metabolism and cancer presents new opportunities for understanding biology and for translating knowledge for therapeutic and diagnostic gain. To this end, we offer a unique combination of state of the art instrumentation, leading technical know-how, computational modeling and software development capabilities, and biological expertise in metabolic pathway regulation in normal and cancer biology.
Metabolite profiling (of 300 metabolites that covers cover most of cancer biology) and flux analysis, when combined with bioinformatics and scientific expertise, are powerful approaches that we are disseminating across the DCI and Duke communities.
Liquid Chromatography :: High Resolution Mass spectrometer :: Speed Vaccum :: Nitrogen dryer :: Multiplexed tissue homogenizer :: Computational capabilities and data analytics
The Integrative Metabolomics shared resource is available to Duke investigators. If demand for facility services exceeds current capacity, Duke Cancer Institute members will receive first priority. Interested researchers can contact shared resource personnel to initiate shared resource activity.
Duke Cancer Institute constellates the world-class resources of Duke University, Duke Health and the Duke Comprehensive Cancer Center into a collaborative powerhouse. We are poised to drive a paradigm shift in the way long-established cancer centers and institutes have been waging this war.Learn More