Lars Grimm
Positions:
Associate Professor of Radiology
Radiology, Breast Imaging
School of Medicine
Member of the Duke Cancer Institute
Duke Cancer Institute
School of Medicine
Education:
B.S. 2004
Stanford University
M.D. 2009
Yale University School of Medicine
M.H.S. 2009
Yale University
Residency, Diagnostic Radiology
Duke University School of Medicine
Fellowship, Radiology, Breast Imaging
Duke University School of Medicine
Grants:
Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Administered By
Radiology, Breast Imaging
Role
Principal Investigator
Start Date
End Date
Prediction of upstaging DCIS to invasive disease: performance comparison between breast radiologists and computer vision algorithms
Administered By
Radiology, Breast Imaging
Awarded By
Radiological Society of North America
Role
Principal Investigator
Start Date
End Date
Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Administered By
Radiology, Breast Imaging
Awarded By
ECOG-ACRIN Medical Research Foundation Inc.
Role
Principal Investigator
Start Date
End Date
Mixed Methods Study of Trainee Perceptions of Radiology with a Focus on Gender and Racial Inequality
Administered By
Radiology, Breast Imaging
Awarded By
Association of University Radiologists Research and Education Foundation
Role
Principal Investigator
Start Date
End Date
Machine Learning for Risk-Adjusted Breast MRI Screening
Administered By
Radiology, Breast Imaging
Awarded By
City College of New York
Role
Principal Investigator
Start Date
End Date
Publications:
Communicating With Breast Imaging Patients During the COVID-19 Pandemic: Impact on Patient Care and Physician Wellness
Objective: Assess the impact of COVID-19 on patient-breast radiologist interactions and evaluate the relationship between safety measure-constrained communication and physician wellbeing. Methods: A 41-question survey on the perceived effect of COVID-19 on patient care was distributed from June 2020 to September 2020 to members of the Society of Breast Imaging and the National Consortium of Breast Centers. Non-radiologists and international members were excluded. Anxiety and psychological distress scores were calculated. A multivariable logistic model was used to identify demographic and mental health factors associated with responses. Results: Five hundred twenty-five surveys met inclusion criteria (23% response rate). Diminished ability to fulfill patients' emotional needs was reported by 46% (221/479), a response associated with younger age (OR, 0.8 per decade; P<0.01), higher anxiety (OR, 2.3; P<0.01), and higher psychological distress (OR, 2.2; P=0.04). Personal protective equipment made patient communication more difficult for 88% (422/478), a response associated with younger age (OR, 0.8 per decade; P=0.008), female gender (OR, 1.9; P<0.01), and greater anxiety (OR, 2.6; P=0.001). The inability to provide the same level of care as prior to COVID-19 was reported by 37% (177/481) and was associated with greater anxiety (OR, 3.4; P<0.001) and psychological distress (OR, 1.7; P=0.03). Conclusion: The majority of breast radiologists reported that COVID-19 has had a negative impact on patient care. This perception was more likely among younger radiologists and those with higher levels of anxiety and psychological distress.
Authors
MLA Citation
Milch, H. S., et al. “Communicating With Breast Imaging Patients During the COVID-19 Pandemic: Impact on Patient Care and Physician Wellness.” Journal of Breast Imaging, vol. 4, no. 2, Mar. 2022, pp. 144–52. Scopus, doi:10.1093/jbi/wbac005.
URI
https://scholars.duke.edu/individual/pub1513095
Source
scopus
Published In
Journal of Breast Imaging
Volume
4
Published Date
Start Page
144
End Page
152
DOI
10.1093/jbi/wbac005
Response by Authors to Comments on Aminololama-Shakeri et al, “Screening Guidelines and Supplemental Screening Tools: Assessment of the Adequacy of Patient–Provider Discussion”
MLA Citation
Aminololama-Shakeri, Shadi, et al. “Response by Authors to Comments on Aminololama-Shakeri et al, “Screening Guidelines and Supplemental Screening Tools: Assessment of the Adequacy of Patient–Provider Discussion”.” Journal of Breast Imaging, vol. 1, no. 4, Oxford University Press (OUP), Dec. 2019, pp. 277–277. Crossref, doi:10.1093/jbi/wbz070.
URI
https://scholars.duke.edu/individual/pub1430747
Source
crossref
Published In
Journal of Breast Imaging
Volume
1
Published Date
Start Page
277
End Page
277
DOI
10.1093/jbi/wbz070
A Proposal to Define Three New Breast Calcification Shapes: Square, Sandwich, and Teardrop, Pill & Capsule
<jats:title>Abstract</jats:title>
<jats:sec>
<jats:title>Objective</jats:title>
<jats:p>To define and illustrate three new descriptors for microcalcification morphology on mammography, and provide a preliminary assessment of their potential clinical value.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Methods</jats:title>
<jats:p>The institutional review board approved this retrospective study and waived the requirement for informed consent. One thousand consecutive biopsy-proven cases of microcalcifications were retrospectively reviewed by the index study observer, a fellowship-trained breast radiologist blinded to histologic outcome. Each case was evaluated for traditional Breast Imaging Reporting and Data System (BI-RADS) morphology descriptors, as well as for the presence of one of three proposed new calcification morphology descriptors: (1) square, (2) sandwich, and (3) teardrop, pill & capsule. Positive predictive value (PPV) for each proposed shape was calculated. Interobserver variability was calculated on a subset of 200 cases, which were evaluated by two additional breast radiologists blinded to the interpretation of the index observer.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results</jats:title>
<jats:p>Of 1000 cases, 702 (70.2%) were benign, and 298 (29.8%) were malignant. There were 51 (5.1%) square and 60 (6.0%) sandwich calcification cases, which were all benign at biopsy (PPV, 0%). Of the 106 (10.6%) cases that included teardrop, pill & capsule calcifications, 90 were malignant (PPV, 84.9%). Interobserver variability for the traditional BI-RADS morphology descriptors (κ = 0.40) was comparable to observer variability of the proposed new morphologies: square (κ = 0.39), sandwich (κ = 0.47), and teardrop, pill & capsule (κ = 0.49).</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Conclusion</jats:title>
<jats:p>The proposed calcification descriptors square and sandwich-shaped had a PPV of 0%, and they may represent new typically benign morphologies. In contrast, teardrop, pill & capsule–shaped calcifications indicate a higher likelihood of malignancy than that of previously established descriptors.</jats:p>
</jats:sec>
Authors
MLA Citation
Baker, Jay A., et al. “A Proposal to Define Three New Breast Calcification Shapes: Square, Sandwich, and Teardrop, Pill & Capsule.” Journal of Breast Imaging, vol. 1, no. 3, Oxford University Press (OUP), Sept. 2019, pp. 186–91. Crossref, doi:10.1093/jbi/wbz046.
URI
https://scholars.duke.edu/individual/pub1430746
Source
crossref
Published In
Journal of Breast Imaging
Volume
1
Published Date
Start Page
186
End Page
191
DOI
10.1093/jbi/wbz046
Practical Steps to Writing a Scientific Manuscript
<jats:title>Abstract</jats:title>
<jats:p>Writing a scientific manuscript can be a very intimidating process for new writers. However, writing a scientific research article can be broken down into discrete steps to make the process more digestible. Radiology manuscripts have common conventions that differ from research in technical and other medical fields. The practical steps summarized within describe what to do before you start writing, successful writing strategies, and common writing styles. Templates for producing an abstract, introduction, methods, results, and discussion are outlined, along with tips to collect references and produce high quality figures. All writers can benefit from an outside writing perspective, and the practical steps described should ease the transition from a blank page to a finished manuscript.</jats:p>
Authors
Grimm, LJ; Harvey, JA
MLA Citation
Grimm, Lars J., and Jennifer A. Harvey. “Practical Steps to Writing a Scientific Manuscript.” Journal of Breast Imaging, vol. 4, no. 6, Oxford University Press (OUP), Dec. 2022, pp. 640–48. Crossref, doi:10.1093/jbi/wbac059.
URI
https://scholars.duke.edu/individual/pub1554320
Source
crossref
Published In
Journal of Breast Imaging
Volume
4
Published Date
Start Page
640
End Page
648
DOI
10.1093/jbi/wbac059
What's in a Name? Moving Away From "Women's Imaging".
Authors
Lenderink-Carpenter, A; Grimm, LJ
MLA Citation
Lenderink-Carpenter, Amanda, and Lars J. Grimm. “What's in a Name? Moving Away From "Women's Imaging".” J Am Coll Radiol, vol. 19, no. 12, Dec. 2022, pp. 1336–37. Pubmed, doi:10.1016/j.jacr.2022.08.015.
URI
https://scholars.duke.edu/individual/pub1554219
PMID
36265813
Source
pubmed
Published In
Journal of the American College of Radiology : Jacr
Volume
19
Published Date
Start Page
1336
End Page
1337
DOI
10.1016/j.jacr.2022.08.015

Associate Professor of Radiology
Contact:
Dept of Radiology, Box 3808, Durham, NC 27710