Shannon McCall

Overview:

As Vice Chair for Translational Research in the Department of Pathology, I am involved in numerous translational cancer research projects that rely on the study of human biological samples.  I am the director of the Duke BioRepository & Precision Pathology Center (Duke BRPC), a shared resource of the School of Medicine and the Duke Cancer Institute.  I serve as the PI for the National Cancer Institute's Cooperative Human Tissue Network Southern Division (a five-year UM1 grant), which lives in the Duke BRPC.  My own area of research interest is gastrointestinal tract metaplasias and their relationship to carcinogenesis, particularly in the upper GI tract.

Positions:

Associate Professor of Pathology

Pathology
School of Medicine

Associate Professor in Surgery

Surgery, Surgical Sciences
School of Medicine

Member of the Duke Cancer Institute

Duke Cancer Institute
School of Medicine

Education:

B.S. 1996

North Carolina State University

M.D. 2000

Duke University

Anatomic and Clinical Pathology, American Board of Pathology (ABPath)

American Board of Pathology

Clinical Informatics, American Board of Pathology (ABPath)

American Board of Pathology

Resident, Pathology

Duke University

Chief Resident, Pathology

Duke University

Grants:

Mutation analysis of pap smear samples and associated tissues for ovarian cancer diagnostics

Administered By
Pathology
Awarded By
Genendeavor LLC
Role
Principal Investigator
Start Date
End Date

Cooperative Human Tissue Network Support through Duke's BioRepository & Precision Pathology Center

Administered By
Pathology
Awarded By
National Institutes of Health
Role
Principal Investigator
Start Date
End Date

The genetics of hepatosplenic T cell lymphoma

Administered By
Medicine, Hematologic Malignancies and Cellular Therapy
Awarded By
National Institutes of Health
Role
Co Investigator
Start Date
End Date

Empowering Duke's Precision Pathology Center with Quantitative Image Analysis to Support Discovery, Diagnostic Assay Development, and Immune Cell Monitoring

Administered By
Pathology
Awarded By
North Carolina Biotechnology Center
Role
Principal Investigator
Start Date
End Date

Lung Squamous Cell Carcinoma: Validation of Molecular Signatures of Prognosis

Awarded By
University of Colorado - Denver
Role
Pathologist
Start Date
End Date

Publications:

Abstract B035: Identification of a tumor cell adaptive stress response signaling pathway, which drives aggressive breast cancer phenotype and therapeutic resistance, in African American patients with locally advanced breast cancer subtypes

Authors
Devi, GR; Al Abo, M; Gearhart-Serna, L; Geradts, J; McCall, SJ; Krishnamurthy, S
MLA Citation
Devi, Gayathri R., et al. “Abstract B035: Identification of a tumor cell adaptive stress response signaling pathway, which drives aggressive breast cancer phenotype and therapeutic resistance, in African American patients with locally advanced breast cancer subtypes.” Poster Presentations  Proffered Abstracts, American Association for Cancer Research, 2020. Crossref, doi:10.1158/1538-7755.disp19-b035.
URI
https://scholars.duke.edu/individual/pub1466477
Source
crossref
Published In
Poster Presentations Proffered Abstracts
Published Date
DOI
10.1158/1538-7755.disp19-b035

Abstract B071: Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients

Authors
Deveaux, AE; Zhang, D; Al Abo, M; Barrett, NJ; Kittles, RA; Owzar, K; McCall, SJ; Crawford, J; Patierno, SR; Clarke, JM; Freedman, JA
MLA Citation
Deveaux, April E., et al. “Abstract B071: Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients.” Poster Presentations  Proffered Abstracts, American Association for Cancer Research, 2020. Crossref, doi:10.1158/1538-7755.disp18-b071.
URI
https://scholars.duke.edu/individual/pub1466478
Source
crossref
Published In
Poster Presentations Proffered Abstracts
Published Date
DOI
10.1158/1538-7755.disp18-b071

Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients

Authors
Deveaux, AE; Zhang, D; Al Abo, M; Barrett, NJ; Kittles, RA; Owzar, K; McCall, SJ; Crawford, J; Patierno, SR; Clarke, JM; Freedman, JA
MLA Citation
Deveaux, April E., et al. “Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients.” Cancer Epidemiology Biomarkers & Prevention, vol. 29, no. 6, 2020.
URI
https://scholars.duke.edu/individual/pub1466479
Source
wos-lite
Published In
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Volume
29
Published Date

Abstract A114: Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry

Authors
Patierno, BM; Glover, W; Foo, W-C; Somarelli, JA; Ware, KE; Xu, L; Li, Y; Chen, X; George, DJ; Kittles, RA; Armstrong, AJ; McCall, SJ; Huang, J; Freedman, JA; Patierno, SR; Hsu, DS
MLA Citation
Patierno, Brendon M., et al. “Abstract A114: Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry.” Poster Presentations  Proffered Abstracts, American Association for Cancer Research, 2020. Crossref, doi:10.1158/1538-7755.disp18-a114.
URI
https://scholars.duke.edu/individual/pub1466480
Source
crossref
Published In
Poster Presentations Proffered Abstracts
Published Date
DOI
10.1158/1538-7755.disp18-a114

Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry

Authors
Patierno, BM; Glover, W; Foo, W-C; Somarelli, JA; Ware, KE; Xu, L; Li, Y; Chen, X; George, DJ; Kittles, RA; Armstrong, AJ; McCall, SJ; Huang, J; Freedman, JA; Patierno, SR; Hsu, DS
MLA Citation
Patierno, Brendon M., et al. “Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry.” Cancer Epidemiology Biomarkers & Prevention, vol. 29, no. 6, 2020.
URI
https://scholars.duke.edu/individual/pub1466481
Source
wos-lite
Published In
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Volume
29
Published Date

Research Areas:

Ampulla of Vater
Apoptosis
Bevacizumab
Bile Ducts
Biological Markers
Biopsy
Biopsy, Needle
Cell Differentiation
Cell Line
Cell Nucleus
Cell Proliferation
Cell Survival
Cells, Cultured
Colorectal Neoplasms
Colorectal Neoplasms, Hereditary Nonpolyposis
Cytochrome P-450 CYP2E1
Endocytosis
Epithelial Cells
Epithelial-Mesenchymal Transition
Gene Deletion
Gene Expression Profiling
Gene Expression Regulation
Gene Expression Regulation, Developmental
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Hedgehog Proteins
Homeodomain Proteins
Humans
Hydroxyproline
Immunohistochemistry
Kruppel-Like Transcription Factors
Lasers
Mesenchymal Stromal Cells
Mesoderm
Microdissection
Mutation
Nuclear Proteins
Oligonucleotides, Antisense
Oligoribonucleotides, Antisense
Oncogenes
Organoplatinum Compounds
Pancreaticoduodenectomy
Pancreatitis
Pilot Projects
Prognosis
Protein Isoforms
Proteome
Proto-Oncogene Proteins
Proto-Oncogene Proteins B-raf
Pyrimidines
RNA, Messenger
Receptors, Cell Surface
Recombinant Proteins
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Stromal Cells
Thiazoles
Tissue Donors
Tumor Markers, Biological
Tumor Necrosis Factor-alpha
Wnt Proteins
Xenograft Model Antitumor Assays
ras Proteins