Rendon Nelson

Overview:

Diagnostic Imaging of the Liver; Specifically the Detection and Characterization of Focal and Diffuse Processes by US, CT and MRI.
Percutaneous Image-Guided Thermal Ablation of Hepatic and Renal Tumors

Positions:

Reed and Martha Rice Distinguished Professor of Radiology, in the School of Medicine

Radiology, Abdominal Imaging
School of Medicine

Professor of Radiology

Radiology, Abdominal Imaging
School of Medicine

Professor in the Department of Mechanical Engineering and Materials Science

Mechanical Engineering and Materials Science
Pratt School of Engineering

Member of the Duke Cancer Institute

Duke Cancer Institute
School of Medicine

Education:

M.D. 1980

Loma Linda University, School of Medicine

M.D. 0

Kent State University

Grants:

Optimization of radiofrequency ablation with electrically conductive particles

Administered By
Radiology, Interventional Radiology
Awarded By
National Institutes of Health
Role
Collaborator
Start Date
End Date

Large aperture and wideband modular ultrasound arrays for the diagnosis of liver cancer

Administered By
Biomedical Engineering
Awarded By
Stanford University
Role
Co Investigator
Start Date
End Date

Improved Image Quality of Focal Liver Lesions Using the Coherence of Ultrasound

Administered By
Biomedical Engineering
Awarded By
National Institutes of Health
Role
Co Investigator
Start Date
End Date

Image Rich Radiology Reports: A Value-Based Model to Improve Clinical Workflow

Administered By
Radiology, Abdominal Imaging
Awarded By
Radiological Society of North America
Role
Collaborator
Start Date
End Date

Characterization of Early Anti-Angiogensis Treatment Effects in Colorectal Carcinoma Using High-Resolution Dynamic Contrast-Enhanced Ultrasound and Magnetic Resonance Imaging

Administered By
Radiology, Abdominal Imaging
Awarded By
Radiological Society of North America
Role
Principal Investigator
Start Date
End Date

Publications:

How frequently does hepatocellular carcinoma develop in at-risk patients with a negative liver MRI examination with intravenous Gadobenate dimeglumine?

OBJECTIVE: To determine the rate of development of clinically significant liver nodules (LR-4, LR-5, LR-M) after a negative MRI in an HCC screening population. METHODS: This retrospective study included patients at risk of developing HCC requiring imaging surveillance who had undergone multiphase Gadobenate dimeglumine-enhanced MRI that was negative and had follow up LI-RADS compliant multiphase CTs or MRIs for at least 12 months or positive follow-up within 12 months. Follow-up examinations were classified as negative (no nodules or only LR-1 nodules) or positive (nodule other than LR-1). Time-to-first positive examination, types of nodules, and cumulative incidence of nodule development were recorded. RESULTS: 204 patients (mean age 58.9 ± 10.2 years, 128 women), including 172 with cirrhosis, were included. Based CT/MRI follow-up (median 35 months, range 12-80 months), the overall cumulative incidence of developing a nodule was 10.5%. Cumulative incidence of nodule development was: 0.5% at 6-9 months and 2.1% at 12 ± 3 months, including one LR-4 nodule, one LR-M nodule, and two LR-3 nodules. The cumulative incidence of clinically significant nodule development was 1.1% at 9-15 months. 70% (143/204) of patients also underwent at least one US follow-up, and no patient developed a positive US examination following index negative MRI. CONCLUSION: Clinically significant liver nodules develop in 1.1% of at-risk patients in the first year following negative MRI. While ongoing surveillance is necessary for at-risk patients, our study suggests than longer surveillance intervals after a negative MRI may be reasonable and that further research is needed to explore this possibility.
Authors
Zaki, IH; Shropshire, E; Zhang, S; Xiao, D; Wildman-Tobriner, B; Marin, D; Gupta, RT; Erkanli, A; Nelson, RC; Bashir, MR
MLA Citation
Zaki, Islam H., et al. “How frequently does hepatocellular carcinoma develop in at-risk patients with a negative liver MRI examination with intravenous Gadobenate dimeglumine?Abdom Radiol (Ny), vol. 46, no. 3, Mar. 2021, pp. 969–78. Pubmed, doi:10.1007/s00261-020-02771-5.
URI
https://scholars.duke.edu/individual/pub1461101
PMID
32951065
Source
pubmed
Published In
Abdom Radiol (Ny)
Volume
46
Published Date
Start Page
969
End Page
978
DOI
10.1007/s00261-020-02771-5

Hemodialysis catheter integrity during mechanical power injection of iodinated contrast medium for computed tomography angiography.

PURPOSE: CT angiography (CTA) requires vascular access with flow rates of 5-7 mL/s. Hemodialysis (HD) is performed at 6-10 mL/s. The purpose of our study is to evaluate the structural integrity of HD catheters in the administration of contrast media via a mechanical power injector under varying conditions. METHODS: Four HD catheters were evaluated in an in vitro study. Tested were contrast media type (iopamidol 300 and 370 mgI/mL), temperature (25 and 37 °C), catheter diameter (14 Fr to 16 Fr all with double-lumen capacity), catheter length (19-32 cm), and simultaneous double-lumen or single-lumen injection within each of the catheters. Peak plateau pressures (psi) were recorded with flow rates from 5 to 20 mL/s in 5 mL/s increments. In total, 864 unique injections were performed. RESULTS: No catheter failure (bulging/rupture) was observed in 864 injections. Maximum pressure for single-lumen injection was 51.7 psi (double-lumen: 26.3 psi). Peak pressures were significantly lower in simultaneous double-lumen vs. single-lumen injections (p < 0.001) and low vs. high viscosity contrast media (p < 0.001). Neither larger vs. smaller diameter lumens (p = 0.221) nor single-lumen injection in arterial vs. venous (p = 0.834) were significantly different. CONCLUSION: HD catheters can be used to safely administer iodinated contrast media via mechanical power injection in in vitro operating conditions. Maximum peak pressure is below the manufacturer's 30 psi limit at flow rates up to 20 mL/s in double-lumen injections and up to 10 mL/s in single-lumen injections, which is higher than the usual maximum of 8 mL/s for CT angiography in clinical settings.
Authors
Schwartz, FR; Lewis, DS; King, AE; Murphy, FG; Howle, LE; Kim, CY; Nelson, RC
MLA Citation
Schwartz, Fides R., et al. “Hemodialysis catheter integrity during mechanical power injection of iodinated contrast medium for computed tomography angiography.Abdom Radiol (Ny), Jan. 2021. Pubmed, doi:10.1007/s00261-020-02905-9.
URI
https://scholars.duke.edu/individual/pub1470719
PMID
33386919
Source
pubmed
Published In
Abdom Radiol (Ny)
Published Date
DOI
10.1007/s00261-020-02905-9

Neuroradiology case of the day. Von Hippel-Lindau disease.

Authors
Enterline, DS; Davey, NC; Tien, RD; Garabedian, V
MLA Citation
Enterline, D. S., et al. “Neuroradiology case of the day. Von Hippel-Lindau disease.Ajr Am J Roentgenol, vol. 165, no. 1, July 1995, pp. 212–13. Pubmed, doi:10.2214/ajr.165.1.7785604.
URI
https://scholars.duke.edu/individual/pub711495
PMID
7785604
Source
pubmed
Published In
Ajr. American Journal of Roentgenology
Volume
165
Published Date
Start Page
212
End Page
213
DOI
10.2214/ajr.165.1.7785604

Genitourinary case of the day. Renal lymphangiomatosis.

Authors
Leder, RA
MLA Citation
Leder, R. A. “Genitourinary case of the day. Renal lymphangiomatosis.Ajr Am J Roentgenol, vol. 165, no. 1, July 1995, pp. 197–98. Pubmed, doi:10.2214/ajr.165.1.7785592.
URI
https://scholars.duke.edu/individual/pub714958
PMID
7785592
Source
pubmed
Published In
Ajr. American Journal of Roentgenology
Volume
165
Published Date
Start Page
197
End Page
198
DOI
10.2214/ajr.165.1.7785592

Gastrointestinal case of the day. Obturator hernia causing small bowel obstruction.

Authors
Keogan, MT; Paulson, EK
MLA Citation
Keogan, M. T., and E. K. Paulson. “Gastrointestinal case of the day. Obturator hernia causing small bowel obstruction.Ajr Am J Roentgenol, vol. 165, no. 1, July 1995, pp. 192–93. Pubmed, doi:10.2214/ajr.165.1.7785588.
URI
https://scholars.duke.edu/individual/pub951916
PMID
7785588
Source
pubmed
Published In
Ajr. American Journal of Roentgenology
Volume
165
Published Date
Start Page
192
End Page
193
DOI
10.2214/ajr.165.1.7785588