Momen Wahidi

Overview:

Emphysema, Lung Nodules, Lung Cancer, Bronchoscopy, Pleural Diseases

Positions:

Professor of Medicine

Medicine, Pulmonary, Allergy, and Critical Care Medicine
School of Medicine

Member of the Duke Cancer Institute

Duke Cancer Institute
School of Medicine

Education:

M.D. 1992

Damascus University, Faculty of Medicine (Syria)

Preliminary Internship, Medicine

Abington Memorial Hospital Dixon, School of Nursing

Medical Resident, Medicine

Indiana University at Indianapolis

Chief Medical Resident, Medicine

Indiana University at Indianapolis

Fellow in Pulmonary and Critical Care Medicine, Medicine

Duke University

Grants:

Percepta R-1 Registry

Administered By
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Awarded By
Veracyte, Inc.
Role
Principal Investigator
Start Date
End Date

All In One: Multicenter prospective trial of Electromagnetic Bronchoscopic and Electromagnetic Transthoracic approaches for the biopsy of peripheral pulmonary nodules

Administered By
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Awarded By
Veran Medical Technologies, Inc
Role
Principal Investigator
Start Date
End Date

CPR-05394 ANET Electrosurgery Applicator Pilot Evaluation Study

Administered By
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Awarded By
Olympus Corporation
Role
Principal Investigator
Start Date
End Date

19-Gauge needle aspiration of thoracic lymph nodes

Administered By
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Awarded By
Spiration, Inc.
Role
Principal Investigator
Start Date
End Date

EAST 2: Elaluation of the Archimedes System for Transparenchymal Nodule Access 2

Administered By
Medicine, Pulmonary, Allergy, and Critical Care Medicine
Awarded By
Broncus Medical, Inc.
Role
Principal Investigator
Start Date
End Date

Publications:

AABIP Evidence-informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.

BACKGROUND: While the efficacy of Indwelling pleural catheters for palliation of malignant pleural effusions is supported by relatively robust evidence, there is less clarity surrounding the postinsertion management. METHODS: The Trustworthy Consensus-Based Statement approach was utilized to develop unbiased, scientifically valid guidance for the management of patients with malignant effusions treated with indwelling pleural catheters. A comprehensive electronic database search of PubMed was performed based on a priori crafted PICO questions (Population/Intervention/Comparator/Outcomes paradigm). Manual searches of the literature were performed to identify additional relevant literature. Dual screenings at the title, abstract, and full-text levels were performed. Identified studies were then assessed for quality based on a combination of validated tools. Appropriateness for data pooling and formation of evidence-based recommendations was assessed using predetermined criteria. All panel members participated in development of the final recommendations utilizing the modified Delphi technique. RESULTS: A total of 7 studies were identified for formal quality assessment, all of which were deemed to have a high risk of bias. There was insufficient evidence to allow for data pooling and formation of any evidence-based recommendations. Panel consensus resulted in 11 ungraded consensus-based recommendations. CONCLUSION: This manuscript was developed to provide clinicians with guidance on the management of patients with indwelling pleural catheters placed for palliation of malignant pleural effusions. Through a systematic and rigorous process, management suggestions were developed based on the best available evidence with augmentation by expert opinion when necessary. In addition, these guidelines highlight important gaps in knowledge which require further study.
Authors
Miller, RJ; Chrissian, AA; Lee, YCG; Rahman, NM; Wahidi, MM; Tremblay, A; Hsia, DW; Almeida, FA; Shojaee, S; Mudambi, L; Belanger, AR; Bedi, H; Gesthalter, YB; Gaynor, M; MacKenney, KL; Lewis, SZ; Casal, RF
MLA Citation
Miller, Russell J., et al. “AABIP Evidence-informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.J Bronchology Interv Pulmonol, vol. 27, no. 4, Oct. 2020, pp. 229–45. Pubmed, doi:10.1097/LBR.0000000000000707.
URI
https://scholars.duke.edu/individual/pub1456733
PMID
32804745
Source
pubmed
Published In
J Bronchology Interv Pulmonol
Volume
27
Published Date
Start Page
229
End Page
245
DOI
10.1097/LBR.0000000000000707

Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy. A Multicenter Study.

Rationale: Patients with malignant or paramalignant pleural effusions (MPEs or PMPEs) may have tunneled pleural catheter (TPC) management withheld because of infection concerns from immunosuppression associated with antineoplastic therapy.Objectives: To determine the rate of infections related to TPC use and to determine the relationship to antineoplastic therapy, immune system competency, and overall survival (OS).Methods: We performed an international, multiinstitutional study of patients with MPEs or PMPEs undergoing TPC management from 2008 to 2016. Patients were stratified by whether or not they underwent antineoplastic therapy and/or whether or not they were immunocompromised. Cumulative incidence functions and multivariable competing risk regression analyses were performed to identify independent predictors of TPC-related infection. Kaplan-Meier method and multivariable Cox proportional hazards modeling were performed to examine for independent effects on OS.Results: A total of 1,408 TPCs were placed in 1,318 patients. Patients had a high frequency of overlap between antineoplastic therapy and an immunocompromised state (75-83%). No difference in the overall (6-7%), deep pleural (3-5%), or superficial (3-4%) TPC-related infection rates between subsets of patients stratified by antineoplastic therapy or immune status was observed. The median time to infection was 41 (interquartile range, 19-87) days after TPC insertion. Multivariable competing risk analyses demonstrated that longer TPC duration was associated with a higher risk of TPC-related infection (subdistribution hazard ratio, 1.03; 95% confidence interval [CI], 1.00-1.06; P = 0.028). Cox proportional hazards analysis showed antineoplastic therapy was associated with better OS (hazard ratio, 0.84; 95% CI, 0.73-0.97; P = 0.015).Conclusions: The risk of TPC-related infection does not appear to be increased by antineoplastic therapy use or an immunocompromised state. The overall rates of infection are low and comparable with those of immunocompetent patients with no relevant antineoplastic therapy. These results support TPC palliation for MPE or PMPEs regardless of plans for antineoplastic therapy.
Authors
Wilshire, CL; Chang, S-C; Gilbert, CR; Akulian, JA; AlSarraj, MK; Asciak, R; Bevill, BT; Davidson, KR; Delgado, A; Grosu, HB; Herth, FJF; Lee, HJ; Lewis, JE; Maldonado, F; Ost, DE; Pastis, NJ; Rahman, NM; Reddy, CB; Roller, LJ; Sanchez, TM; Shojaee, S; Steer, H; Thiboutot, J; Wahidi, MM; Wright, AN; Yarmus, LB; Gorden, JA
MLA Citation
Wilshire, Candice L., et al. “Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy. A Multicenter Study.Ann Am Thorac Soc, vol. 18, no. 4, Apr. 2021, pp. 606–12. Pubmed, doi:10.1513/AnnalsATS.202007-886OC.
URI
https://scholars.duke.edu/individual/pub1462483
PMID
33026887
Source
pubmed
Published In
Annals of the American Thoracic Society
Volume
18
Published Date
Start Page
606
End Page
612
DOI
10.1513/AnnalsATS.202007-886OC

Cone beam navigation bronchoscopy: the next frontier.

Navigation bronchoscopy has reached a new horizon in its evolution. Combining with real-time imaging modalities, such as cone-beam computed tomography (CBCT) and augmented fluoroscopy (AF), navigation success can finally be confirmed with high degree of accuracy in real-time. With utilization of this modality, additional clinical observations are being made to help address the CT-body divergence problem and further improve navigation accuracy. This review focuses on description of CBCT navigation technique, provide tips on addressing CT-Body divergence, and review evidence for CBCT applications in navigation bronchoscopy.
Authors
Cheng, GZ; Liu, L; Nobari, M; Miller, R; Wahidi, M
MLA Citation
Cheng, George Z., et al. “Cone beam navigation bronchoscopy: the next frontier.J Thorac Dis, vol. 12, no. 6, June 2020, pp. 3272–78. Pubmed, doi:10.21037/jtd.2020.03.85.
URI
https://scholars.duke.edu/individual/pub1450752
PMID
32642250
Source
pubmed
Published In
Journal of Thoracic Disease
Volume
12
Published Date
Start Page
3272
End Page
3278
DOI
10.21037/jtd.2020.03.85

Key Highlights From the American Association for Bronchology and Interventional Pulmonology Evidence-Informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.

Authors
Miller, CRJ; Chrissian, AA; Lee, YCG; Rahman, NM; Wahidi, MM; Tremblay, A; Hsia, DW; Almeida, FA; Shojaee, S; Mudambi, L; Belanger, AR; Bedi, H; Gesthalter, YB; Gaynor, M; MacKenney, KL; Lewis, SZ; Casal, RF
MLA Citation
URI
https://scholars.duke.edu/individual/pub1464367
PMID
33152319
Source
pubmed
Published In
Chest
Volume
159
Published Date
Start Page
920
End Page
923
DOI
10.1016/j.chest.2020.09.282

Advanced Diagnostic and Therapeutic Bronchoscopy: Technology and Reimbursement.

Advanced interventional pulmonary procedures of the airways, pleural space, and mediastinum continue to evolve and be refined. Health-care, finance, and clinical professionals are challenged by both the indications and related coding complexities. As the scope of interventional pulmonary procedures expands with advanced technique and medical innovation, program planning and ongoing collaboration among clinicians, finance executives, and reimbursement experts are key elements for success. We describe advanced bronchoscopic procedures, appropriate Current Procedural Terminology coding, valuations, and necessary modifiers to fill the knowledge gap between basic and advanced procedural coding. Our approach is to balance the description of procedures with the associated coding in a way that is of use to the proceduralist, the coding specialist, and other nonclinical professionals.
Authors
Desai, NR; Gildea, TR; Kessler, E; Ninan, N; French, KD; Merlino, DA; Wahidi, MM; Kovitz, KL
MLA Citation
Desai, Neeraj R., et al. “Advanced Diagnostic and Therapeutic Bronchoscopy: Technology and Reimbursement.Chest, Feb. 2021. Pubmed, doi:10.1016/j.chest.2021.02.008.
URI
https://scholars.duke.edu/individual/pub1474742
PMID
33581100
Source
pubmed
Published In
Chest
Published Date
DOI
10.1016/j.chest.2021.02.008